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Warning [2] Undefined array key "avatartype" - Line: 889 - File: global.php PHP 8.0.30 (Linux)
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Warning [2] Undefined variable $myalerts_js - Line: 101 - File: global.php(953) : eval()'d code PHP 8.0.30 (Linux)
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Warning [2] Undefined variable $unreadreports - Line: 107 - File: global.php(956) : eval()'d code PHP 8.0.30 (Linux)
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Warning [2] Undefined variable $myalerts_modal - Line: 79 - File: global.php(1056) : eval()'d code PHP 8.0.30 (Linux)
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Warning [2] Undefined array key 1 - Line: 1449 - File: inc/functions.php PHP 8.0.30 (Linux)
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Warning [2] Undefined array key 1 - Line: 1449 - File: inc/functions.php PHP 8.0.30 (Linux)
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Warning [2] Undefined property: MyLanguage::$ratings_update_error - Line: 5 - File: showthread.php(772) : eval()'d code PHP 8.0.30 (Linux)
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Warning [2] Undefined variable $postsdone - Line: 906 - File: showthread.php PHP 8.0.30 (Linux)
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Warning [2] Undefined array key 10424 - Line: 912 - File: showthread.php PHP 8.0.30 (Linux)
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/showthread.php 1643 errorHandler->error
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/showthread.php 924 buildtree
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/showthread.php 1643 errorHandler->error
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/showthread.php 924 buildtree
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covid19 vaccine
#75
Data Leak Shows Regulators Had Major Concerns About Pfizer’s mRNA Vaccine

Leaked documents show that some early commercial batches of Pfizer-BioNTech’s COVID-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform.
As it conducted its analysis of the Pfizer-BioNTech COVID-19 vaccine in December, the European Medicines Agency (EMA) was the victim of a cyberattack. More than 40 megabytes of classified information from the agency’s review were published on the dark web, and several journalists — including from The BMJ — and academics worldwide were sent copies of the leaks. They came from anonymous email accounts and most efforts to interact with the senders were unsuccessful. None of the senders revealed their identity, and the EMA says it is pursuing a criminal investigation.
The BMJ has reviewed the documents, which show that regulators had major concerns over unexpectedly low quantities of intact mRNA in batches of the vaccine developed for commercial production.
EMA scientists tasked with ensuring manufacturing quality — the chemistry, manufacturing and control aspects of Pfizer’s submission to the EMA — worried about “truncated and modified mRNA species present in the finished product.” Among the many files leaked to The BMJ, an email dated Nov. 23 by a high ranking EMA official outlined a raft of issues. In short, commercial manufacturing was not producing vaccines to the specifications expected, and regulators were unsure of the implications. EMA responded by filing two “major objections” with Pfizer, along with a host of other questions it wanted addressed.

Read More: Data Leak Shows Regulators Had Major Concerns About Pfizer’s mRNA Vaccine
  


Messages In This Thread
covid19 vaccine - by remap1 - 11-17-2020, 02:23 PM
RE: covid19 vaccine - by remap1 - 11-17-2020, 08:40 PM
RE: covid19 vaccine - by awakened53 - 12-05-2020, 10:55 AM
RE: covid19 vaccine - by awakened53 - 12-07-2020, 01:37 AM
RE: covid19 vaccine - by awakened53 - 12-25-2020, 10:28 AM
RE: covid19 vaccine - by awakened53 - 12-28-2020, 12:03 PM
RE: covid19 vaccine - by Steve - 12-28-2020, 01:40 PM
RE: covid19 vaccine - by awakened53 - 12-29-2020, 01:10 AM
RE: covid19 vaccine - by awakened53 - 12-30-2020, 01:21 AM
RE: covid19 vaccine - by awakened53 - 12-30-2020, 07:27 PM
RE: covid19 vaccine - by awakened53 - 01-04-2021, 04:58 AM
RE: covid19 vaccine - by Steve - 01-04-2021, 11:56 AM
RE: covid19 vaccine - by awakened53 - 01-05-2021, 09:43 PM
RE: covid19 vaccine - by awakened53 - 01-06-2021, 03:41 PM
RE: covid19 vaccine - by awakened53 - 01-07-2021, 12:52 AM
RE: covid19 vaccine - by Steve - 01-07-2021, 05:55 PM
RE: covid19 vaccine - by Steve - 01-08-2021, 11:22 AM
RE: covid19 vaccine - by awakened53 - 01-08-2021, 03:12 PM
RE: covid19 vaccine - by awakened53 - 01-09-2021, 06:06 PM
RE: covid19 vaccine - by awakened53 - 01-11-2021, 05:45 PM
RE: covid19 vaccine - by Steve - 01-13-2021, 07:46 AM
RE: covid19 vaccine - by Steve - 01-13-2021, 09:05 PM
RE: covid19 vaccine - by awakened53 - 01-14-2021, 02:57 PM
RE: covid19 vaccine - by awakened53 - 01-15-2021, 01:01 PM
RE: covid19 vaccine - by awakened53 - 01-18-2021, 03:54 AM
RE: covid19 vaccine - by awakened53 - 01-18-2021, 06:37 PM
RE: covid19 vaccine - by Steve - 01-18-2021, 09:48 PM
RE: covid19 vaccine - by awakened53 - 01-20-2021, 12:48 PM
RE: covid19 vaccine - by Steve - 01-24-2021, 08:27 AM
RE: covid19 vaccine - by Steve - 01-27-2021, 01:39 PM
RE: covid19 vaccine - by Steve - 01-28-2021, 01:18 PM
RE: covid19 vaccine - by awakened53 - 01-28-2021, 01:19 PM
RE: covid19 vaccine - by Steve - 01-29-2021, 10:52 AM
RE: covid19 vaccine - by Steve - 01-30-2021, 11:56 AM
RE: covid19 vaccine - by Steve - 02-01-2021, 11:57 AM
RE: covid19 vaccine - by Steve - 02-03-2021, 11:59 AM
RE: covid19 vaccine - by awakened53 - 02-03-2021, 02:52 PM
RE: covid19 vaccine - by Steve - 02-04-2021, 10:01 AM
RE: covid19 vaccine - by awakened53 - 02-05-2021, 03:40 PM
RE: covid19 vaccine - by Steve - 02-09-2021, 07:15 AM
RE: covid19 vaccine - by awakened53 - 02-09-2021, 04:10 PM
RE: covid19 vaccine - by Steve - 02-11-2021, 08:34 AM
RE: covid19 vaccine - by Abdel - 02-11-2021, 04:40 PM
RE: covid19 vaccine - by awakened53 - 02-11-2021, 06:26 PM
RE: covid19 vaccine - by awakened53 - 02-11-2021, 10:35 PM
RE: covid19 vaccine - by Steve - 02-14-2021, 06:10 PM
RE: covid19 vaccine - by awakened53 - 02-15-2021, 06:31 PM
RE: covid19 vaccine - by Davor from Croatia - 02-15-2021, 06:40 PM
RE: covid19 vaccine - by Steve - 02-16-2021, 10:25 AM
RE: covid19 vaccine - by awakened53 - 02-18-2021, 05:45 PM
RE: covid19 vaccine - by Steve - 02-18-2021, 09:31 PM
RE: covid19 vaccine - by awakened53 - 02-19-2021, 09:38 AM
RE: covid19 vaccine - by Steve - 02-19-2021, 01:57 PM
RE: covid19 vaccine - by Steve - 02-20-2021, 06:18 PM
RE: covid19 vaccine - by awakened53 - 02-20-2021, 06:35 PM
RE: covid19 vaccine - by awakened53 - 02-22-2021, 03:06 PM
RE: covid19 vaccine - by awakened53 - 02-23-2021, 12:42 PM
RE: covid19 vaccine - by Steve - 02-23-2021, 08:05 PM
RE: covid19 vaccine - by awakened53 - 02-24-2021, 07:27 PM
RE: covid19 vaccine - by Steve - 02-26-2021, 01:31 PM
RE: covid19 vaccine - by awakened53 - 02-26-2021, 09:57 PM
RE: covid19 vaccine - by Steve - 02-27-2021, 12:37 PM
RE: covid19 vaccine - by awakened53 - 02-28-2021, 09:54 AM
RE: covid19 vaccine - by awakened53 - 03-01-2021, 12:50 PM
RE: covid19 vaccine - by Steve - 03-09-2021, 08:40 AM
RE: covid19 vaccine - by awakened53 - 03-09-2021, 06:07 PM
RE: covid19 vaccine - by Steve - 03-11-2021, 07:54 AM
RE: covid19 vaccine - by awakened53 - 03-11-2021, 01:26 PM
RE: covid19 vaccine - by Steve - 03-12-2021, 09:21 AM
RE: covid19 vaccine - by awakened53 - 03-12-2021, 04:58 PM
RE: covid19 vaccine - by Steve - 03-14-2021, 11:54 AM
RE: covid19 vaccine - by awakened53 - 03-14-2021, 04:27 PM
RE: covid19 vaccine - by awakened53 - 03-15-2021, 06:36 PM
RE: covid19 vaccine - by awakened53 - 03-16-2021, 10:10 PM
RE: covid19 vaccine - by awakened53 - 03-17-2021, 11:45 PM
RE: covid19 vaccine - by Steve - 03-18-2021, 10:16 AM
RE: covid19 vaccine - by awakened53 - 03-19-2021, 12:11 AM
RE: covid19 vaccine - by Steve - 03-19-2021, 09:44 PM
RE: covid19 vaccine - by awakened53 - 03-20-2021, 07:37 PM
RE: covid19 vaccine - by awakened53 - 03-21-2021, 11:03 PM
RE: covid19 vaccine - by Steve - 03-22-2021, 01:31 PM
RE: covid19 vaccine - by awakened53 - 03-25-2021, 12:58 PM
RE: covid19 vaccine - by awakened53 - 03-27-2021, 12:47 PM
RE: covid19 vaccine - by awakened53 - 03-28-2021, 01:27 PM
RE: covid19 vaccine - by awakened53 - 03-30-2021, 01:52 PM
RE: covid19 vaccine - by awakened53 - 03-30-2021, 04:39 PM
RE: covid19 vaccine - by Steve - 03-31-2021, 06:11 PM
RE: covid19 vaccine - by Steve - 04-01-2021, 03:57 PM
RE: covid19 vaccine - by awakened53 - 04-07-2021, 01:34 PM
RE: covid19 vaccine - by Steve - 04-08-2021, 12:01 PM
RE: covid19 vaccine - by awakened53 - 04-09-2021, 12:29 PM
RE: covid19 vaccine - by awakened53 - 04-11-2021, 12:41 PM
RE: covid19 vaccine - by awakened53 - 04-12-2021, 08:51 AM
RE: covid19 vaccine - by awakened53 - 04-17-2021, 04:39 PM
RE: covid19 vaccine - by awakened53 - 04-19-2021, 03:28 PM
RE: covid19 vaccine - by awakened53 - 04-20-2021, 05:25 PM
RE: covid19 vaccine - by Steve - 04-28-2021, 03:03 PM
RE: covid19 vaccine - by awakened53 - 04-30-2021, 04:27 PM
RE: covid19 vaccine - by awakened53 - 05-03-2021, 11:01 PM
RE: covid19 vaccine - by awakened53 - 05-14-2021, 01:09 PM
RE: covid19 vaccine - by awakened53 - 05-24-2021, 09:55 AM
RE: covid19 vaccine - by awakened53 - 05-26-2021, 05:18 PM
RE: covid19 vaccine - by awakened53 - 06-01-2021, 05:31 PM
RE: covid19 vaccine - by awakened53 - 06-02-2021, 11:41 AM
RE: covid19 vaccine - by Steve - 06-03-2021, 06:57 AM
RE: covid19 vaccine - by awakened53 - 06-18-2021, 04:40 PM
RE: covid19 vaccine - by Steve - 06-21-2021, 09:19 AM
RE: covid19 vaccine - by awakened53 - 07-02-2021, 08:32 AM
RE: covid19 vaccine - by awakened53 - 07-06-2021, 08:40 AM
RE: covid19 vaccine - by awakened53 - 07-11-2021, 12:38 PM
RE: covid19 vaccine - by awakened53 - 07-12-2021, 10:50 AM
RE: covid19 vaccine - by awakened53 - 07-15-2021, 10:32 AM
RE: covid19 vaccine - by awakened53 - 07-16-2021, 12:36 PM
RE: covid19 vaccine - by awakened53 - 07-20-2021, 05:41 PM
RE: covid19 vaccine - by awakened53 - 07-29-2021, 12:40 PM
RE: covid19 vaccine - by awakened53 - 08-03-2021, 09:24 PM
RE: covid19 vaccine - by awakened53 - 08-21-2021, 08:22 AM
RE: covid19 vaccine - by awakened53 - 08-24-2021, 02:03 PM
RE: covid19 vaccine - by awakened53 - 07-05-2022, 10:54 PM
RE: covid19 vaccine - by awakened53 - 08-18-2022, 06:23 PM
RE: covid19 vaccine - by awakened53 - 10-27-2022, 02:16 PM

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