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A history of infertility vaccines – until COVID-19
#1
From the start of this pandemic, I’ve thought that the main purpose of the corona vaccines is to make women infertile in the latest depopulation scheme.
If these experimental mRNA-vaccines indeed permanently alter the DNA, this infertility would also be for life.


The short story is that the COVID-19 vaccine learns the immune system to fight against spike proteins, including syncytin-1, which is essential for the formation of the human placenta.
An immune response against the spike protein, could also attack synctin-1, which would cause infertility in women: https://2020news.de/en/dr-wodarg-and-dr-...-petition/
(https://archive.is/e9yHJ)


From the petition of German doctor Wolfgang Wodarg and British doctor Michael Yeadon.
Quote:XI. Several vaccine candidates are expected to induce the formation of humoral antibodies against spike proteins of SARS-CoV-2. Syncytin-1 (see Gallaher, B., “Response to nCoV2019 Against Backdrop of Endogenous Retroviruses” - http://virological.org/t/response-to-nco...iruses/396), which is derived from human endogenous retroviruses (HERV) and is responsible for the development of a placenta in mammals and humans and is therefore an essential prerequisite for a successful pregnancy, is also found in homologous form in the spike proteins of SARS viruses.
There is no indication whether antibodies against spike proteins of SARS viruses would also act like anti-Syncytin-1 antibodies. However, if this were to be the case this would then also prevent the formation of a placenta which would result in vaccinated women essentially becoming infertile. To my knowledge, Pfizer/BioNTech has yet to release any samples of written materials provided to patients, so it is unclear what, if any, information regarding (potential) fertility-specific risks caused by antibodies is included.

According to section 10.4.2 of the Pfizer/BioNTech trial protocol, a woman of childbearing potential (WOCBP) is eligible to participate if she is not pregnant or breastfeeding, and is using an acceptable contraceptive method as described in the trial protocol during the intervention period (for a minimum of 28 days after the last dose of study intervention).
This means that it could take a relatively long time before a noticeable number of cases of postvaccination infertility could be observed.
https://healthimpactnews.com/wp-content/...hibits.pdf
(http://web.archive.org/web/2020120515113...hibits.pdf)


The UK has already approved the genocidal Pfizer coronavirus vaccine, with the first victims to be poisoned as early as next week. The official documents confirm that the vaccines haven’t been properly tested.
Because side effects of the vaccine on pregnant women aren’t known, the vaccine shouldn’t be given to pregnant women.
Quote:There are no or limited amount of data from the use of COVID-19 mRNA Vaccine BNT162b2. Animal reproductive toxicity studies have not been completed. COVID-19 mRNA Vaccine BNT162b2 is not recommended during pregnancy.
For women of childbearing age, pregnancy should be excluded before vaccination. In addition, women of childbearing age should be advised to avoid pregnancy for at least 2 months after their second dose.
http://web.archive.org/web/2020120500003...accine.pdf
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#2
The following article is the most “informative” I’ve found on the hypothesis that the COVID-19 vaccines will sterilise women by mobilising the immune system against syncytins.
It’s not a “good” article because the writer ignores all of the evidence against the coronavirus “pandemic” and the vaccine trials, with the following conclusion.
Quote:In short, the claim that the vaccines for COVID-19/SARS-CoV-2 will cause infertility because of some kind of crossreactive immune response between the spike protein antigens and syncytin proteins is baseless.
https://archive.is/7Bmc2


What the writer of the previous propaganda piece forgets to take into account is that the vaccine trials were/are a complete charade, so that it’s far from “baseless” to assume that these vaccines cause severe harm.
Basically these experimental mRNA vaccines have been approved without knowing their efficacy or adverse effects.

By staging the pandemic these psychopaths have effectively bypassed doing any form of decent study into the efficacy and adverse effects of these experimental mRNA-vaccines.
With the result that big pharma can directly start their sick experiments on the population. Human experiments like these are in violation of the Nuremberg code.
It can’t be seen as voluntarily “consent”, if people get misinformed about these vaccines, and on top of that will be forced to take them, because it is required for work (besides for travelling, or doing “normal” things like going to a bar or restaurant).


The following confirms that we’re talking about an experiment on humans on a massive scale, which involves “tracking systems” to “ensure that patients each get two doses of the same vaccine and to monitor them for adverse health effects”.
Maybe somebody should point out that these health effects should be monitored BEFORE everybody gets poisoned with the vaccines in an independent scientific trial…

Official OWS show that the vaccine human guinea pigs will be monitored for 24 months after the first dose of a COVID-19 vaccine through a “pharmacovigilance system” (what?!?).
OWS describes one of its “four key tenets” as “traceability” to: 1) “confirm which of the approved vaccines were administered regardless of location (private/public)”; 2) to send a “reminder to return for second dose”; and 3) to “administer the correct second dose”.

Despite claims that the “pharmacovigilance surveillance system” would intimately involve the FDA. In September, top FDA officials complained they were barred from attending OWS meetings and could not explain the operation’s organisation because it is essentially a top-secret Pentagon program: https://www.thelastamericanvagabond.com/...two-years/
(https://archive.is/HwRgJ)
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#3
Vaccinations with the DNA-altering corona vaccines have begun in the UK…


Most people will quickly dismiss the “conspiracy theories” that the not properly tested corona vaccines will sterilise women, because we are too smart to be fooled like that.
There is hard evidence that the same psychopaths that make a nice profit from shoving the sustainable development down our throats, are very concerned with the problem of overpopulation and consider vaccines (and health care in general) as the solution to too much useless eaters.


In 1972, the United Nations, World Health Organization (WHO) and World Bank collaborated on the “Special Programme of Research, Development and Research Training in Human Reproduction (HRP)” to “coordinate, promote, conduct, and evaluate research in human reproduction”.
In 1972, the WHO founded the “Task Force on Vaccines for Fertility Regulation” to produce an hCG-laced anti-fertility vaccine.
This has continued to produce vaccines for “fertility regulation”, see the following report from 1991: https://www.ncbi.nlm.nih.gov/pubmed/1874951
(http://archive.is/HG8pN)


In 1973, Stevens and Chrystle published a report on anti-fertility vaccines, which showed that hCG can be used to sterilise women.
Here’s the abstract of “Effects of Immunization with Hapten-Coupled HCG on the Human Menstrual Cycle” (1973): http://journals.lww.com/greenjournal/Abs..._on.1.aspx


In 1976 another study on hCG was published by A. Pala et al “Immunization with hapten-coupled hCG-β subunit and its effect on the menstrual cycle” (1976), only the abstract: http://www.contraceptionjournal.org/arti...0009-3/pdf


And then there’s the infamous 1974 National Security Council Document 20506: Implications of Worldwide Population Growth for U.S. Security and Overseas Interests. Written by none other than Nobel Prize winner for peace, Henry Kissinger...
They identified India, Bangladesh, Pakistan, Nigeria, Mexico, Indonesia, Brazil, Philippines, Thailand, Egypt, Turkey, Ethiopia and Columbia as problematic:
Quote:29. While specific goals in this area are difficult to state, our aim should be for the world to achieve a replacement level of fertility, (a two-child family on the average), by about the year 2000. This will require the present 2 percent growth rate to decline to 1.7 percent within a decade and to 1.1 percent by 2000.
(…)
In less developed countries growth rates average about 2.4 percent. For the People's Republic of China, with a massive, enforced birth control program, the growth rate is estimated at under 2 percent. India's is variously estimated from 2.2 percent, Brazil at 2.8 percent, Mexico at 3.4 percent, and Latin America at about 2.9 percent. African countries, with high birth as well as high death rates, average 2.6 percent; this growth rate will increase as death rates go down.
(…)
Steady increases in the number of acceptors at family planning facilities indicate a likelihood of some fertility reduction in Thailand, Indonesia, the Philippines, Colombia, and other countries which have family planning programs. On the other hand, there is little concrete evidence of significant fertility reduction in the populous countries of India, Bangladesh, Pakistan, etc.1
(...)
concentrating on the education and indoctrination of the rising generation of children regarding the desirability of smaller family size.
(…)
Considerable reduction in infant and child mortality is possible through improvement in nutrition, inoculations against diseases, and other public health measures if means can be devised for extending such services to neglected LDC populations on a low-cost basis. It often makes sense to combine such activities with family planning services in integrated delivery systems in order to maximize the use of scarce LDC financial and health manpowder (sic.) resources (See Section IV). In addition, providing selected health care for both mothers and their children can enhance the acceptability of family planning by showing concern for the whole condition of the mother and her children and not just for the single factor of fertility.
(…)
Research indicates that female wage employment outside the home is related to fertility reduction. Programs to increase the women's labor force participation must, however, take account of the overall demand for labor; this would be a particular problem in occupations where there is already widespread unemployment among males. But other occupations where women have a comparative advantage can be encouraged.
(…)
d. Sterilization of men and women has received wide-spread acceptance in several areas when a simple, quick, and safe procedure is readily available. Female sterilization has been improved by technical advances with laparoscopes, culdoscopes, and greatly simplifies abdominal surgical techniques. Further improvements by the use of tubal clips, trans-cervical approaches, and simpler techniques can be developed. For men several current techniques hold promise but require more refinement and evaluation. Approx. Increased Cost $6 million annually.
https://archive.is/ay8aG


The Gates Foundation is heavily involved in vaccinating the world.
In the following 29:32 video Bill Gates, in a presentation for the TED 2010 conference, explains that we need “solutions” that will make the “miracle” of zero CO2 emission happen. By 2050 we must realize an 80% reduction in CO2 emission...
Gates explains that “people” (P) are at the basis of this “problem” (4:00-4:55)
It includes the following notorious quote: “The world today has 6.8 billion people … that’s headed up to about 9 billion. Now if we do a really great job on new vaccines, health care, reproductive health services, we could lower that by perhaps 10 or 15 percent.
https://www.youtube.com/watch?v=JaF-fq2Zn7I
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#4
The GAVI Alliance was founded in 2000 with the help of the Gates Foundation, other donors include: the Rockefeller foundation, UNICEF, World Health Organization (WHO), and World Bank.
GAVI has the goal of vaccinating the entire Third World.
Obviously part of the plan is to reduce fertility for depopulation purposes.

The research by Jurriaan Maessen, is an important source for information on anti-fertility vaccines.
There are not only vaccines to reduce fertility, but pregnant women are forced to get vaccinated, which has caused abortions in Thailand and the Philippines: http://www.oldthinkernews.com/2010/09/04...reduction/


Jurriaan Maessen noted, that Rockefeller had already conceived sterilisation vaccines way back in the 1930s:
Quote:Rockefeller Foundation minion Max Mason, who acted as president in the mid-1930s, on multiple occasions expressed his master’s desire for an “anti-hormone” that would reduce fertility worldwide. Now keep in mind, this is more than 35 years before the Foundation actually mentioned funding “anti-fertility vaccines” in subsequent annual reports from 1969 onward.
.
In 1973, the Mexican birth rate was unashamedly described as a “Population Bomb” in the state media.
[Image: 0808f2026c3827fec85d6aba92c29480a33f83c1.jpg]

In 1974, a group of Mexicans found out (or at least suspected) that a group disguised as inoculation teams “who looked like foreigners” gave shots at schools to sterilise their children. The teams were escorted by the police.
Vaccination was never done at Mexican schools, so the parents had a good reason to be suspicious.

The “rumours” began in the north in Nuevo Leon, and then reached Mexico City, where thousands of angry parents “in slum areas” stormed and barricaded schools, and removed their children from them. Some 35-40% of elementary kids were absent Wednesday of that week.
According to the National Action party: “The rare vaccine, until now never used, much less as part of a campaign which appears to cover many parts of the republic, is given to each child in three places: the umbilicis, the chest, and the spinal column”.
The government denied the “rumours”, claiming that sterilisation vaccines don’t exist.
[Image: de9961fca057d31f9d91181596e9ebec0a82baa6.jpg]

Coercive sterilisations under the banner of “family planning” were taking place all over the globe in 1974. In April 1974, it was reported that the government had sterilised some 1,204 girls and boys under the age of 21 at federally funded clinics across the country. This included a ten year old, an eleven year old, and ten 13 year olds.
The US government had funded sterilisations on: poor women, the mentally ill, deaf, blind, with Epilepsy, and others who were considered “unfit” to have babies: http://archive.is/zxQ34
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#5
A 2010 study conducted by the Philippine Medical Association (PMA) indicated that Philippine women were “unwittingly vaccinated against their own children”.
By linking hCG with tetanus antigens in a vaccine, researchers fool a woman’s immune system into producing antibodies against hCG, which makes her allergic to her own embryo.
Once her immune system is sufficiently stimulated against hCG, the pregnant woman will spontaneously abort the embryo: https://www.pop.org/bad-blood-in-the-philippines/


The following report shows that influenza vaccination causes abortions in lab animals; Ayoub & Yazbak “Influenza Vaccination During Pregnancy: A Critical Assessment of the Recommendations of the Advisory Committee on Immunization Practices (ACIP)” (2006). [Image: pregna1.jpg]
http://www.whale.to/vaccine/ayoub.pdf


The 1978 WHO task force “Evaluating the safety and efficacy of placental antigen vaccines for fertility regulation”, shows initiatives to use vaccines for reduced fertility.
It even shows that they already knew then that hCG can cause abortions.
Quote:Although substantial progress has been made over the last few years in the provision of family planning services to many of the World's populations, there is still an urgent need for a greater variety of safe, effective and acceptable methods of fertility regulation to meet widely differing personal, cultural and service requirements.
Immunization as a prophylactic measure is now so widely accepted that it has been suggested that one method of fertility regulation which might have wide appeal as well as great ease of service delivery would be an anti-fertility vaccine.
(…)
In principle, anti-fertility vaccines may: (a) prevent sperm transport and/or fertilization; (b) prevent or disrupt implantation; and © prevent blastocyst development.
(…)
Several potential complications have to be considered upon immunization of humans with immunogenic conjugates of HCG-derived antigens. Some of these hazards are related to potential disruption of the endocrinological balance and maternal-embryonal relationships; others are related to the possible autoimmunity induced with human-derived material as an autoantigen. Consideration of these potential hazards should provide guidelines for design and evaluation of animal and human studies.
https://www.ncbi.nlm.nih.gov/pmc/article...5-0170.pdf
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#6
Sen. Schumer calls for replacement of Americans who can't have babies after mRNA jabs 

Yes, you are being replaced. Once derided as a racist conspiracy theory, "replacement theory" is not only confirmed but even touted by Democrat Sen. Chuck Schumer who yesterday claimed that millions of illegals must be granted amnesty because the US population "is not reproducing on its own."
Of course, that's because so-called "vaccine" injections -- actually mRNA depopulation bioweapons -- are causing widespread abortions, stillbirths, infertility and deaths. As expert analyst Ed Dowd told this reporter yesterday, post-vaccine excess mortality across the population at large is running around 32 percent, meaning an extra 2,400+ Americans are dying each day thanks to the mRNA jabs.
Democrats are actively calling for dead, aborted or still birthed Americans to be replaced by illegals... all while they push more jabs to achieve more deaths of the American people.

Get the full details in today's feature podcast here.

https://www.brighteon.com/9057a26a-bd64-...2c971962e0
#7
In May 2020 (?), a video was uploaded to and deleted by Youtube that a GSK whistleblower exposed that the COVID-19 vaccine will make 97% of the women infertile.
The video isn't very informative, but there are some interesting follow-up articles and another video on these sterilisation vaccines (11:21).
https://www.bitchute.com/video/IalsQvC0XIdl/


In Kenya in October 2015, pharmaceutical company Agriq-Quest Ltd had their licence revoked for trying to expose that half a million girls were sterilised using anti-HCG (Beta-HCG) in tetanus vaccineS.

Here is a more recent documentary on this diabolical affair...
The interviews with the African whistleblowers - including Kenyan doctor Stephen Karanja, who died in April 2021, reportedly of COVID - is very interesting.
https://www.bitchute.com/video/RA59YPPHZjZe/


A study from 1994, presenting "evidence of the feasibility of a vaccine for control of human fertility” describes how the HCG sterilisation vaccines work:
Quote:We report here results of clinical trials on a birth control vaccine, consisting of a heterospecies dimer of the beta subunit of human chorionic gonadotropin (hCG) associated noncovalently with the alpha subunit of ovine luteinizing hormone and conjugated to tetanus and diphtheria toxoids as carriers, that induces antibodies of high avidity (K(a) approximately 10(10) M-1) against hCG.
Whilst, the antibody response declines with time; fertility was regained when titers fell to < 35 ng/ml.
As fertility came back, "booster shots" are needed!

This explains that because it doesn't give other indications of sterilisation, it could be used covertly:
Quote:An advantage in choosing hCG as a target for immunocontraception is that its inactivation would not interfere with other physiological processes in the female, such as ovulation and production of sex steroid hormones.
.
Another this study from 1989 about “Vaccines are under development for the control of fertility in males and females" adds the following on hCG vaccines:
Quote:Vaccines inducing antibodies against the human chorionic gonadotropin have gone through phase I trials with satisfactory results. A vaccine producing a consistently bioeffective antibody response against gonadotropin-releasing hormone is ready for phase I/II clinical trials in patients of carcinoma of prostate after due experimenation in animals and toxicology studies. Research to identify sperm antigens for incorporation into second generation vaccines is in progress.
https://healingoracle.ch/2020/05/13/coro...fertility/
(https://archive.is/frARP)


The following is a typical "debunking" story, that does such a poor job that this actually makes the original, deleted video more convincing to me...
There is however some additional information on the original deleted Youtube video.

Maybe the following (61 from 63) is where the 97% figure comes from.
Quote:The speaker also says that GSK tested 63 women with a vaccine containing anti-hGC antigens that resulted in 61 becoming infertile (5m29s). Those statistics also appear in the 1989 paper and an older one, by one of the same researchers and are not related to GSK.
.
See the following example.
Quote:In the video the speaker says he wants to “look at who is running the vaccine trial” and names Dr Andrew Preston from the University of Bath, saying he “spoke on television the other night”. Phoenix says Dr Preston received a £28 million grant from the Bill and Melinda Gates Foundation, which he claims is “interfering and trying to manipulate” human vaccine trials."
It goes on to explain that this is all preposterous while admitting that Andrew Preston had an important role in the vaccine trials, and admitting that Preston received (part of) a £28 million grant from amongst others the Gates Foundation for another vaccine trial...

Even more ridiculous is that because one of the referenced studies in the video concerns cancer vaccines, this is no smoking gun (I really don't understand the "debunking argument")!
Quote:Prof Griffin said the 1989 paper referred to in the video “was obviously very deliberately about a vaccine for contraception or cancer research”.
This is all the more suspicious against the background that HPV vaccines (that have been marketed as cancer vaccines) are known to reduce fertility in women:
https://www.aap.com.au/covid-19-vaccine-...from-1989/
(https://archive.is/0iq13)


If you want to check the named 1989 study for yourself here it is: http://archive.vn/VIpgr


The cancer study suggests that GnRH vaccines could make men so femine that this would effectively sterilise them.
Quote:The GnRH vaccine has the potential to be effective in both men and women. A study in male rats using diphtheria toxoid as the GnRH vaccine carrier reveals that antibody titers rise, testosterone levels fall, weight of testis decreases, and the prostate disappears.
https://pubmed.ncbi.nlm.nih.gov/1618603/
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#8
Here is another scientific-looking article on infertility vaccines (Immunocontraceptives).


See the following excerpts...
Quote:A novel contraceptive approach that is gaining substantial attention is “immunocontraception” targeting gamete production, gamete outcome, or gamete function. Amongst these, use of sperm antigens (gamete function) seems to be an exciting and feasible approach. However, the variability of immune response and time lag to attain titer among vaccinated individuals after active immunization has highlighted the potential relevance of preformed antibodies in this league. This review is an attempt to analyze the current status and progress of immunocontraceptive approaches with respect to their establishment as a future fertility control agent.
(...)

A novel contraceptive approach that is gaining substantial attention is immunocontraception, which is the use of contraceptive vaccines (CVs) or preformed antibodies to prevent fertilization. As with the conventional vaccines, CVs utilise the body's defense system to wedge an essential step in the reproductive process [6]. A successful contraceptive vaccine must meet a number of criteria; it must be reliable, easy to administer, safe, affordable, widely acceptable, and capable of evoking homogeneous response and must bestow a high level of contraceptive efficacy.
There are three major categories involved in the development of CVs including gamete production, namely, gonadotropin releasing hormone (GnRH), follicle stimulating hormone (FSH), and luteinizing hormone (LH); gamete outcome, namely, human chorionic gonadotropin (hCG), or gamete function, namely, zona pellucida (ZP) and sperm antigens [7]. Of all, validation and practicability for the development of antisperm vaccines targeting prefertilization events seem to be much more encouraging and promising.
(...)

When GnRH vaccine was tested on human subjects, including breastfeeding women by The National Institute of Immunology, India, and the Population Control Council, USA, the vaccine essentially resulted in castration and halted testosterone production [11]. However, these results were accompanied with impotence and loss of body hair in case of men and affected menopause in women [12]. Hence, an analogue of GnRH was prepared by linking with different carriers in an attempt to make improved vaccine [7].
(...)

Immunization of male bonnet monkeys with ovine FSH resulted in testicular dysfunction, oligozoospermia, and subsequent infertility [25]. It was noteworthy that infertility was not associated with any change in testosterone levels thus adding an additional advantage of using FSH based vaccine.
(...)

Immunization of adult female sheep (ewe) with LH prohibited pregnancy in all the animals during two breeding seasons.
(...)

Anti-hCG vaccine was the first and only birth control vaccine to go through Phase II efficacy trials successfully. The use of vaccine in sexually active women prevented them from becoming pregnant [31].
(...)

The term gamete function is associated with the two main cells participating in gamete formation, that is, sperm and ovum. This approach targets the zona antigens of egg and surface antigens of sperm. The targets being nonhormonal provide much better safety upon other approaches. Exploiting ZP antigens as immunocontraceptive may interfere with the normal production of egg in female while sperm-based vaccine will be used in female reproductive tract to block fertilization by interfering with sperm movement or function.
(...)

Further studies revealed that the infertility induced in immunized female rabbits was irreversible which could not be restored even after the administration of exogenous gonadotropins. Histological examination of ovaries showed the destruction of oocytes in all the growing follicles along with the depletion of resting follicles [38]. This observation indicated that the infertility was a consequence of ovarian dystrophy rather than inhibition of sperm-oocyte interaction.
.

Kiranjeet Kaur and Vijay Prabha - Immunocontraceptives: New Approaches to Fertility Control (2014): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119744/
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#9
The Indian (?) Satish Gupta for more than 20 years has done research on infertility vaccines to decimate the human population.
Basically this confirms just about all the "insane" conspiracy theories that vaccines are developed for genocide purposes...
.
Quote:The rising global human population, particularly in the developing countries, has necessitated the need to develop new safer methods of contraception. Fertility regulation by vaccines, which otherwise have been used primarily to provide protection against subsequent infection, is an interesting proposition. Vaccines regulating fertility can be easily integrated into the vaccine delivery infrastructure for diseases, which exists in most of the developing countries.
(...)

However, in-situ hybridization of cynomologous monkey ovaries with digoxigenin-labelled cDNA probes specific for the mRNA encoding for ZP1, ZP2 and ZP3 revealed the presence of mRNA encoding ZP2 (ZPA) in growing follicles at all stages and in the granulosa cells of mature pre-ovulatory follicles (Martinez et al., 1996).
(...)

For the development of a human fertility control vaccine, the most important criterion lies in the definition of antigenic determinants on the ZP glycoproteins that would induce a protective contraceptive response without affecting normal ovarian functions. Due to their fine specificity, MAb are suitable probes to define biofunctional antigenic determinants.
(...)

To overcome the problems of limited availability of ZP proteins from ovaries and possible contamination with ovarian proteins, attempts have been made by several groups to express ZP proteins by recombinant DNA technology.
(...)

Cloning, sequencing and expression of these glycoproteins by DNA recombinant technology have provided further insights into their structure and functions. The availability of recombinant ZP glycoproteins/proteins free from contamination of ovarian tissue antigens, thus avoiding dependence on ovaries as the source material to isolate ZP glycoproteins, will help in testing their efficacy to regulate fertility.
.
Satish K. Gupta, et al. - Prospects of zona pellucida glycoproteins as immunogens for contraceptive vaccine (1997): https://academic.oup.com/humupd/article-...030311.pdf
(http://web.archive.org/web/2021021417204...AdM3Mz4X9Q)


In a follow-up report Satish Gupta, et al. (2003), described.

Sterilisation vaccine trials on women;
That porcine zona pellucida vaccine were used to sterilise monkeys;
That synthetic DNA technology could improve (producing) sterilisation vaccines: http://nopr.niscair.res.in/bitstream/123...82-693.pdf


In 2013, Satish Gupta, et al. elaborated on the previous reports.
.
Quote:The increasing human population, particularly in several developing countries of Asia and Africa, has severe consequences on depletion of natural resources, scarcity of drinking water, threatening food security, in addition to its impact on the environment.
(...)

Contraceptive vaccines can be broadly categorized into three groups. One group of the vaccines aims to inhibit production of gametes (spermatozoa and egg). These vaccines work by immune-mediated neutralization of gonadotropin releasing hormone (GnRH) secreted by hypothalamus. (...) Second group of vaccines involves generating immune response against spermatozoa- or oocyte-specific proteins with an aim to interfere with their functions and hence blocking fertilization process. Third group of vaccines target immune-mediated neutralization of human chorionic gonadotropin (hCG).
(...)

Active immunization of female rhesus monkeys with the β-subunit of ovine LH (β-oLH) led to inhibition of fertility, which was accompanied by reduced progesterone levels during luteal phase.40 The anti-fertility effect mediated by active immunization with β-oLH could be reversed by administration of medroxyprogesterone acetate.41
(...)

However, after two years, in spite of high anti-FSH antibody titers, immunized animals showed return of spermatogenesis with sperm count in the normal range. The sperm morphology, motility and their ability to penetrate zona-free hamster eggs was normal.45 In another study, active immunization of male bonnet monkeys with oFSH led to a significant decrease in the sperm count in the semen ejaculate, within 150 d post-immunization.46 Immunization with oFSH had no significant effect on testosterone levels and animals had normal libido. The immunized male monkeys when used for mating with normal females, failed to impregnate suggesting that this immunization procedure led to infertility. The block in fertility was reversible as concomitant with the decline in the anti-oFSH antibody levels, animals regained fertility.47 Active immunization with oFSH did not lead to any side effects.47
(...)

The results from initial Phase-I studies on oFSH-based contraceptive vaccine in men are encouraging. However, the potential of FSH and/or its receptor based contraceptive vaccines warrant further investigations to establish a workable proposition for achieving contraception without any untoward side-effects.
(...)

Observed infertility was invariably associated with ovarian dystrophy accompanied by follicular attresia. However, use of highly purified native porcine zona proteins supplemented with adjuvants other than complete Freund’s adjuvant led to a significant decrease in ovarian pathology.98-100
(...)

However, β-hCG based contraceptive vaccine, only one that has been evaluated in humans, has not shown contraceptive efficacy that is comparable to any of the other alternative available contraceptive options described above.
(...)

Attempts have been made to address this issue in women immunized with β-hCG based contraceptive vaccine. The anti-fertility effect of the vaccine was reversible as women with low anti-hCG antibody titers conceived and pregnancy progressed to term.150 Children born showed normal early developmental parameters.150
.
Satish K. Gupta, et al. - Milestones in contraceptive vaccines development and hurdles in their application (2013): https://www.tandfonline.com/doi/full/10.4161/hv.27202
(https://archive.is/v7q8B)
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
#10
(01-06-2023, 08:49 PM)Firestarter Wrote: This is all the more suspicious against the background that HPV vaccines (that have been marketed as cancer vaccines) are known to reduce fertility in women (maybe more on that in a next post)
The following “scientific” report from 2017 suggests that the controversial HPV vaccine causes lower birth rates. This study analysed information gathered in National Health and Nutrition Examination Survey, representing 8 million 25 to 29-year-old women in the US between 2007 and 2014.

Birth rates in the US have recently fallen to record lows from 118.1 in 2007 to 104.5 in 2015 per 1000 females aged 25–29.
See the birth rates in the US from 1995 to 2015.
[Image: uteh_a_1477640_f0001_oc.jpeg]

One factor could be the vaccination against the human papillomavirus (HPV) that “coincidentally” was approved by the US Food and Drug Administration in 2006 and recommended for females aged 11–26 (and since 2011 also for males of the same age group).

Adverse effects of the HPV vaccine include menstrual disturbances and mood swings. Shortly after the HPV vaccine was licensed, reports of women experiencing Primary Ovarian Failure (POF) emerged.
The estimated incidence of POF for females under the age of 40 is 1 in 100, but this could be considerably higher because it’s masked by the birth control pill. Between 10% and 30% of women with POF also have (other) autoimmune disorders.

61% of women who had not been poisoned with the HPV vaccine had been pregnant at least once, compared to only 35% of women who were poisoned with the HPV vaccine. The difference was especially large for women that had been married. Of the married women 75% that didn’t get the vaccine gave birth, while only 50% who were poisoned with the HPV vaccine had been pregnant.
The pregnancy frequency decreased with increasing numbers of HPV vaccine shots.

See (part of) Table 3 - Ratios of having been pregnant for women who received an HPV shot versus women who did not.
See (part of) Table 5 - Births of females aged 25–29 in the US, by number of HPV shots.
[Image: 611149dcd85fd619854ff2be0e8cbbb13b2c7deb.png]

This suggests that at least part of the reason for the recent decline in US birth rates is caused by the HPV vaccine. Why did it take so long before this link was found (some studies have even denied this link)?
If all married women had been vaccinated with the HPV vaccine, the number of married women having conceived could have fallen with another 1 million.

There are other (possible) causes for the lower birth rates...
Higher employment rates (of women) decreases birth rates.
No epidemiological study on the influence of Aluminium (a component of vaccines) on fertility exists but Karakis et al in 2014 found an association between prenatal exposure to Aluminium and death of the (unborn) baby.
There could also be a link between Aluminium exposure and POF.

Gayle DeLong – A lowered probability of pregnancy in females in the USA aged 25–29 who received a human papillomavirus vaccine injection (2017): https://www.tandfonline.com/doi/full/10....18.1477640


Does anybody find it surprising that in one of those great examples of "science", the study was "retracted"?!?
The least they could do is come up with a good explanation for deleting the report. Instead they came with the story, we got complaints...
Quote:we were alerted to concerns about the scientific validity of the study...
All of the post-publication reports we received described serious flaws in the statistical analysis and interpretation of the data in this paper, and we have therefore taken the decision to retract it
They forgot to detail a single "flaw" in their motivation...
The Order of the Garter rules the world: https://www.lawfulpath.com/forum/viewtop...5549#p5549
  


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